Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)

Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)

What is Lp-PLA2? Lp-PLA2, also known as platelet-activating factor acetylhydrolase (PAF-AH), was initially identified as the enzyme responsible for hydrolyzing and inactivating the inflammatory phospholipid PAF (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine).1-3 PAF...

Small Dense LDL (sdLDL)

As discussed previously, apoB-containing LDL particles exist as a heterogeneous collection of variable sized particles, from small to large. There are technologies that size or measure peak particle diameters (in Angstroms or nanometers).1,2 Phenotype or Pattern A...
High-Sensitivity C-Reactive Protein (hs-CRP)

High-Sensitivity C-Reactive Protein (hs-CRP)

C-Reactive Protein (CRP) is a blood test in our basic metabolic lab panel. Elevated levels of CRP are very common and most patients in our Tulsa, Oklahoma Functional Medicine Clinic want to know what they can do to reduce it. What is CRP? High sensitivity C-reactive...

Fibrinogen

Fibrinogen is a soluble precursor of the insoluble fibrin, the major component of a blood clot. Fibrinogen is a glycoprotein, which consists of three pairs of polypeptide chains, Aa, Bb, and γ.2   Different ways to measure fibrinogen Several laboratory methods...

Apolipoprotein A-I (ApoA-I)

Test Description Apolipoprotein A-I (apoA-I) is the major protein component of high-density lipoprotein (HDL) in plasma. HDL particles can carry from one to four apoA-I molecules per particle. The liver and intestine synthesize lipid-poor apoA-I. The protein promotes...

High-Density Lipoprotein Particle Number (HDL-P)

The idea that HDL cholesterol is cardioprotective is well accepted. What is not as well appreciated is that, similar to the discordant relationship between the level of LDL‐C and number of low density lipoprotein particles in patients with residual CHD risk, the...