Apolipoprotein A-I (ApoA-I)

Test Description Apolipoprotein A-I (apoA-I) is the major protein component of high-density lipoprotein (HDL) in plasma. HDL particles can carry from one to four apoA-I molecules per particle. The liver and intestine synthesize lipid-poor apoA-I. The protein promotes...

High-Density Lipoprotein Particle Number (HDL-P)

The idea that HDL cholesterol is cardioprotective is well accepted. What is not as well appreciated is that, similar to the discordant relationship between the level of LDL‐C and number of low density lipoprotein particles in patients with residual CHD risk, the...

High-Density Lipoprotein Subclass 2 (HDL2-C)

High density lipoproteins (HDLs) are found in human plasma in the density range 1.063-1.21 g/mL and consist by weight of approximately 50% protein, 25% phospholipid, 20% cholesterol, and 5% triglyceride.4,19 The cholesterol component of HDL has been inversely...

High-Density Lipoprotein (HDL-C)

High-density lipoprotein (HDL) particles, characterized either in terms of cholesterol content or by the major protein constituent, apolipoprotein A-I (apoA-I), have been shown to be inversely related to risk of cardiovascular disease (CVD). In fact studies going back...
Homocysteine

Homocysteine

What is Homocysteine? Homocysteine (Hcy) is a sulfhydryl-containing amino acid produced by intracellular demethylation of the essential amino acid methionine (Met). It is not used to make proteins but as an intermediate in methionine metabolism. What does homocysteine...
Apolipoprotein-B (ApoB)

Apolipoprotein-B (ApoB)

Apolipoprotein B (apoB) is the major protein component of chylomicrons, very low-density lipoproteins (VLDLs), intermediate-density lipoproteins (IDLs), lipoprotein(a) [Lp(a)], and low-density lipoproteins (LDLs), and constitutes 20-25% of the total weight of LDL....