Viagra, and other PDE-5 inhibitors, have been a blockbuster hit since they came out over 15 years ago. They’ve helped numerous men achieve erections that were once lost. However, they don’t work well for some unfortunate men. This is not only troublesome and frustrating but also a concerning finding for these men. This episode discusses why and what is going on.

Hypertension is a common problem and one of the biggest contributors to cardiovascular disease which is the #1 killer of both men and women. There are many causes of hypertension to be certain but did you know that using mouthwash and taking stomach acid lowering medications can actually CAUSE high blood pressure? Yep, its true. In this episode, Diana and Dr Edwards discuss the research as well as the mechanisms of  what actually happens in these cases. Mouthwash, PPIs, and hypertension

Nitric Oxide (NO) is THE chemical you want for cardiovascular health. It is the antithesis of endothelin, aldosterone, and antiotensin-2. It improves oxidative stress, reduces vascular inflammation, as well as vascular immune dysfunction. It is a key component of endothelial function. Endothelial dysfunction precedes cardiovascular disease by decades. Therefore, we want to optimize nitric oxide as early as possible.

The endothelium is the inner most, single-cell layer thick lining of the artery. The function of the endothelium is essential for optimal blood vessel health and blood pressure. When the endothelium is not healthy, or dysfunctional, vascular damage begins.

Our genes contain the biochemistry that makes us unique. We get one set of genes from mom and one set of genes from dad. However, just because we have these genes does not mean they are turned on and active. The expression of these genes are often based on environmental factors.